THE PROBLEMS OF CANCER*
UNDER this title the following remarks were published in the Lancet in 1904 as a summary of a University lecture. The objects in view were to throw some embryological light on the possible lack of import of a practical kind attaching to certain recently published observations on so-called “heterotypic” mitoses or cell-divisions in cancer-cells; to point to the futility of regarding carcinoma as due in origin to some sort of “conjugation” of leucocytes of the body; and, lastly, while insisting upon the fundamental identity of carcinoma and sarcoma, to indicate how the problems of cancer finally ended embryo-logically in those of identical twins and their origin. The import, or absence of import, of the first two—the “heterotype” mitoses and the supposed “conjugation” —has now been generally recognized, and the original position taken up regarding these has been abandoned by official cancer research in Great Britain. As pointed out by Dr. Jacob Wolff (“ Die Lehre von der Krebskrankheit,” vol. i., p. 438), this view of the “conjugation of resting nuclei “—one of them that of a leucocyte—was enunciated originally by Auerbach in 1890, but this fact escaped the notice of the official researchers.
*The Lancet, October, 29, 1904.