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Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 Cohorts...

CONCLUSIONS: The results suggest a reduced incidence of major CHD events at high supplemental vitamin C intakes. The risk reductions at high vitamin E or carotenoid intakes appear small.

"This pooled study shows health benefits at >700 mg vitamin C from supplements compared to no supplementation. This ABSOLUTELY disproves the RDA and the false idea that there is a 200 mg daily limit on health benefits!!!!!!!!!!!!!!" - B Sardi

Urgent Bill Sardi Vitamin C RDA Letter to USA Food and Nutrition Board ...

Over 100 MEDLINE Abstracts That Relate Antioxidant Intake to Heart Disease...




10-YEARS AGO: THE LINUS PAULING LECTURES ON VITAMIN C AND HEART DISEASE...

World's Leading Vitamin C Scientists Blast the Puny Vitamin C RDA...

This book presents an open challenge to the government “experts”, who support the out-of-date RDA approach to nutrition and thereby endanger the health of the entire population.

Download 'Ridiculous Dietary Allowance'

The printed version is in press and will be available shortly for about $15.00.

The Cochrane review by Douglas et al. [1], which is referenced in the Best Practice article by Douglas and Hemilä [2], covers 60 years of research into vitamin C and the common cold. However, the review omits pharmacokinetic data that invalidate the conclusion that vitamin C is ineffective. This conclusion is not derivable from the data presented. The dual-phase pharmacokinetics of vitamin C are described by the dynamic flow model [3,4]. Low gram-level intakes of ascorbate, leading to blood plasma levels below 70 μM/l, have a half-life of 840 days. Higher gram-level intakes have a plasma half-life of 30 minutes [3]. A large oral dose raises blood plasma levels briefly: they reach a peak after two to three hours, before decaying back to baseline. Frequent repeated doses allow sustained high plasma levels of about 250 μM/l [4,5]. Douglas and Hemilä reviewed intakes that transiently raise plasma ascorbate levels above 70 μM/l. A single dose does not raise the median level [6,7]. Daily supplements would, thus, not increase disease resistance to any great degree [3,4]. Single or double doses daily will not increase background plasma levels, regardless of the magnitude of the dose [6,7]. Since plasma ascorbate is at background level for the majority of the day, effects will be minimal. There is widespread confusion about nutritional and pharmacological levels of supplementation [3]. Linus Pauling, typically, described nutritional gram-level doses able to provide a degree of disease prevention [8]. By contrast, pharmacological doses used for treatment are, at minimum, an order of magnitude larger and involve frequent doses. The doses should be at intervals of three hours or less [3]. Treatment doses are described by Cathcart's paper on titration to bowel tolerance [9]. To treat the onset of a cold, the therapy is perhaps a minimum of 10 g of oral ascorbic acid, followed by at least 2 g each hour [3,4]. Douglas and Hemilä give a misleading impression by not making it clear that the doses they consider are not pharmacological. They claim that the results of one study, giving an 8-g dose at the start of symptoms, are tantalising and deserve further assessment. However, once this single dose has been excreted, the protective effects will be lost. During illness, ascorbate is depleted rapidly and higher oral intakes are toleratedup to 200 g per day [9]. It would be surprising if this 8-g dose had a large effect. Studies on ascorbate require appropriate doses. Douglas and Hemilä have only confirmed that 60 years of vitamin C research has largely been wasted because of confusion between nutritional and pharmacological intakes, and because of a misunderstanding of the pharmacokinetics. It is essential that high-dose studies take into account ascorbate's dual-phase pharmacokinetics. The dosing regime should allow sustained high plasma levels to be achieved. The claim that vitamin C cannot prevent or cure the common cold is both premature and unwarranted. Steve Hickey Manchester Metropolitan University Manchester, United Kingdom E-mail: radicalascorbate@yahoo.com

THE VITAMIN C CONTROVERSY IS RESOLVED...

"The most important development in the history of vitamin C." - Owen Fonorow

This new book presents a new model, describing the action of vitamin C in health and disease. It demonstrates conclusively that the establishment has misinterpreted the evidence, potentially resulting in epidemic levels of avoidable disease. [More]

ASCORBATE: The Science of Vitamin C

To be blunt -- the NIH gave a dose of vitamin C, waited until it had been excreted, and then measured blood levels.

This book presents a new model, describing the action of vitamin C in health and disease. It demonstrates conclusively that the establishment has misinterpreted the evidence, potentially resulting in epidemic levels of avoidable disease. The dynamic flow model explains the current results and points the way for future experiments.

The failure of the medical establishment to perform critical follow-up experiments may have resulted in much suffering and countless deaths. As Dr Hickey says, "If this book doesn't shock you, you haven't understood it". For this reason, the book ASCORBATE lists the essential experiments necessary to restore respectability to the scientific evaluation of vitamin C. If even a few of the hypotheses are confirmed, readers will understand why double Nobel Prize winner Dr Linus Pauling was prepared to stake his scientific reputation on ascorbate.

Excerpt:

"A large result was observed in a small group, indicating the possibility of a strong effect. Conversely, if you need a large group to demonstrate the effect, the result is probably less important, as it affects a small proportion of subjects or the consequence is weak. It is easy to see that an experiment with ten subjects is unlikely to give a positive result for a treatment that will cure only one patient in one hundred. With a small group of subjects, you will generally find only the larger effects. "

"Large-scale double-blind mega-studies are the current fashion in medicine. The assumption is made that by increasing the number of subjects, the work somehow becomes more valid. Regrettably, these studies are borderline science, as a large-scale study is difficult to repeat and replication is at the core of the scientific method. Of particular concern are those studies that are so expensive that only pharmaceutical companies are ever likely to perform them. The way studies are financed and the potential source of any experimental bias or error become more important with larger studies, as they are more difficult to replicate. Replication reduces the possibility of bias. A large-scale study giving positive results is less convincing than, say, three smaller, equally positive studies by independent researchers, in different institutions, separately funded and using dissimilar methods."

Observations On the Dose and Administration of Ascorbic Acid When Employed Beyond the Range Of A Vitamin In Human Pathology By Fred Klenner, MD.

1949 - A YEAR IN MEDICINE WHICH WILL LIVE IN INFAMY....

During the 1950s isolated doctors around the world tried Klenners cure. Those who used vitamin C at doses below those recommended by Klenner reported no benefit; those who followed his dosages reported good results... Klenner: "To those who say that Polio is without cure, I say that they lie. Polio in the acute form can be cured in 96 hours or less. I beg of someone in authority to try it." - Robert Landwehr

Ascorbic Acid Orally - NOT for IV!

Dr. Cathcart's

• VIDEO: Intravenous Sodium Ascorbate: Preparation & Use
  
   
• FAMOUS PAPER: Vitamin C, Titrating to Tolerance...
  
  
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Interview with Dr. Thomas Levy...

Vitamin C, Infectious Diseases, and Toxins

Vitamin C, Infectious Diseases, and Toxins by Thomas Levy (Paperback - September 2002)

Citing over 1,200 articles from scientific and medical journals around the world, Levy shows that many viral diseases such as polio, hepatitis, and encephalitis have been consistently cured by high doses of vitamin C given intravenously. While maintaining that lower doses of vitamin C taken by mouth may have little or no effect on many infections, Dr. Levy adds that high enough doses administered directly into the blood can demonstrate clinical effects that border on the unbelievable. He notes that large enough oral doses of vitamin C can prevent many infections, but intravenous dosing is often needed to cure infections already contracted.

Without hedging, Dr. Levy explains why, even in his subtitle, he uses the word "cure" as boldly as Dr. Klenner ever did:

"It is completely appropriate to use the term "cure" when, in fact, the evidence demonstrates that a given medical condition has clearly and repeatedly been cured by a specific therapy. . . Avoiding the use of a term such as "cure" when it is absolutely appropriate does as much harm as using it inappropriately. Not realizing the incredible ability of vitamin C to cure a given infectious disease just perpetuates the usage of so many other needlessly applied toxic drugs and clinical protocols. If the shoe fits, wear it, and if the treatment works, proclaim it." (p 15)

And this is precisely what Dr. Levy does.

"Properly dosed vitamin C will reliably and quickly cure nearly all cases of acute polio and acute hepatitis. Polio babies are completely well in less than a week and hepatitis patients are sick for only a few days, not several months." (p 19)

SCURVY, THE COSMIC CONNECTION

"The atmosphere in those days was quite different from what it is today. The living process developed in an essentially oxygen-free atmosphere. Today the atmosphere contains about 20 percent oxygen, which is a by-product of the chemical reactions of photosynthesis. Early life forms produced so much oxygen that the atmosphere gradually changed from a reducing to an oxidizing one. This oxygen was toxic to living cells, creating the planet's first air-pollution crisis. The situation threatened to kill the living cells that had been so successful up to that point.

Nature developed ascorbic acid to save the living process from extinction. This same procedure occurred many times in subsequent evolutionary crises, so that ascorbic acid became, in a sense, the favorite evolutionary life saver. "

Eight Decades of Scurvy. The Case History of a Misleading Dietary Hypothesis...

Sherry Lewin's Molecular Models

As you look at these pictures of vitamin C models from the Sherry Lewin 1976 book Vitamin C: Its Molecular Biology and Medical Potential, note how the ascorbate is the "hat" that fits on many different organic molecular "heads."

For example, when ascorbate (vitamin C) binds with adrenaline (noradrenaline) it prevents what would otherwise be a rapid breakdown of this hormone. When it binds with a cation of histamine, it fits like a glove, and this may explain why a nasal drip can be stopped within five minutes of ingesting high-dose ascorbic acid.

There is a picture of the arginine "guanidinium group" bound with ascorbate.

Dr. Sydney J Bush. PhD. DOpt. (IOSc. London)

The New Definition of Scurvy...

BREAKTHROUGH: RETINAL PHOTOS CONFIRM VITAMIN C PILLS CAN REVERSE ARTERY DISEASE...

Purchase Sydney Bush's New Book - Now On Sale

Dr. Sydney Bush's passionate tome provides a wealth of information about Vitamin C. Dr. Bush is an optometrist who discovered that the eyes are not only the window to the heart, but they can be used to monitor reversal of heart disease.. He (as have many other eye doctors) has been able to measure the progression of heart disease in the retinal arteries. It is generally accepted by the medical profession that the atherosclerosis eye doctors observe in their patients cannot be reversed. It is medical dogma that arterial plaques always get worse. Dr. Bush discovered that these plaques can be made to go away quite easily! After Dr. Bush saw that it can and was being reversed in his patients on high vitamin C and other nutrients (The so-called Pauling therapy), he became intrigued, informed and tried to spread the word in Britain. He was amazed by the resistance of the medical profession, National Health Service, etc. Just like Linus Pauling before him, Bush hit a brick wall of disbelief and suppression. Dr. Bush's new book is a product of his studies into vitamin C. It is meant to expose the wealth of knowledge about vitamin C that science has uncovered, but that has been deliberately kept from the medical profession.

PRESS RELEASE: RETINAL PHOTOS CONFIRM VITAMIN C PILLS CAN REVERSE ARTERY DISEASE...

Dr. Bush's Web Sites