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Vitamin B3 Beats Superbug. This is another Wow!

Posted: Tue Aug 28, 2012 1:42 pm
by ofonorow
http://www.genengnews.com/gen-news-highlights/superbug-succumbs-to-vitamin-boosted-immune-system/81247237/
New evidence indicates that the vitamin B3 (nicotinamide, NAM) can directly boost the immune system’s ability to fight serious Staphylococcus infections, including MRSA. In vivo studies in mice and in vitro work with human blood have shown that treatment with NAM administered prophylactically or therapeutically enhances the clearance of staphylococcal infection by up to 1,000-fold. The Cedars-Sinai Medical Center team reporting the studies say that the vitamin acts by increasing expression and activity of the myeloid-specific transcription factor CCAAT/enhancer-binding protein ε (C/EBPε) in myeloid cells, and particularly in the neutrophils that were largely responsible for the NAM-related increase in bacterial cell killing


I am not familiar with the idea that vitamin B3 is an immune booster? Can anyone find the dosages?

Re: Vitamin B3 Beats Superbug. This is another Wow!

Posted: Tue Aug 28, 2012 3:19 pm
by Johnwen
showed that NAM treatment in humans at a dose of 10 to 20 mg/kg/d induced neutrophilia in the blood of the patients at days 3 and 7


Here's the full study

http://www.jci.org/articles/view/62070