Let me address the plavix/effient vs. warfarin issue.
I’m thinking giving you links will more fully explain their difference.
First remember as you read Plavix/effient prevent platelet aggregation.
You will see how this works when you read this.
http://en.wikipedia.org/wiki/PlateletNow warfarin reduces another component of the clotting factor that is fibrin.
By not having enough fibrin means the platelet’s sticking together have nothing to bind to that is explained in the following links.
http://en.wikipedia.org/wiki/Coagulatio ... on_cascadehttp://en.wikipedia.org/wiki/WarfarinTo over simplify things I like to use comparisons to something people have seen happen. In this case let’s look at concrete.
The three major components of concrete are Water, Cement, Sand.
Water Being the serum component of the blood.
Cement being the platelet’s.
Sand being the fibrin.
Once mixed together they will solidify even under water.
But if you remove or lessen anyone of the components the best you could hope for is a weak structure at best.
Without enough sand the cement water mix will clump and harden since the cement is sticking to itself and dissolving at the same time and when hardened it will crumble. Add Sand and now it has something to attach to and when hard it has the strength of these tiny rocks holding it together.
Remove the cement or lower it’s amount and you have sand and water and a little bit of glue and you get a compressible clump of beach sand!!
Now lets do things the Plavix/effient Way! First we take our cement and mix it with motor oil. Making sure it gets well oiled. Now we mix our concrete?
Yep! we now have a glob of slippery yuk! That’ll never harden and we do like our bodies do and just toss it out! The Plavix/effient alters the platelets and makes them a slippery substance that prevents them from sticking together.
This is how these drugs work one removes, lowers or alters one component and the other removes, lowers or alters the other. The results are the same No or weak thrombus formation.
Having a weak or frail fibrin can also lead to problems if the slippery substance of the platelets is removed. As the weak fibrin will be looked at as ineffective and will draw the platelets to them in hope of removal but most of the time they just start to clump and problems begin.
This is what the protein S indicates and why it’s necessary to get this some help!!
Bear in mind the actions of these blood components are a necessary component of life and is part of our defensive system that keep us from bleeding to death if we scratch ourselves. As such they are usually only called upon to react if there is a causative action. (Ie. Damage) Be it a leaking artery or a skinned knee Something has to trigger their response. This is where Pauling therapy comes in to help heal the damage before it becomes chronic!
Hematology is a hard 4 year course! So don’t try to get too deep into it, just try to get a grasp on the basic’s and you’ll have a better understanding then a lot of doc’s out there!
So his recalls to the hospital where restenosis of the stent’s, This is a common occurrence and the reason for the development of the DES (drug eluding stent) which buy more time. Once again think Pauling! I’ve seen it work over and over again. His famous words ring true here “Don’t Stop taking it NOT even for a single day!” It has to be something he does everyday without fail!!
Iron: Look for a good Daily Multi with about 18 to 20 Mg of iron which is usually enough if taken daily.
I tried to make this complex subject as simple as possible. Hope it helps in your understanding.
To steal ideas from one person is plagiarism. To steal from many is
research!