High Lp(a), hlcerative colitis, Hasimotos - PT causes bloat

[ofonorow]

My long emails were apparently lost, so, I will explain here in a much shorter email.

Briefly, I have 3 autoimmune conditions: ulcerative colitis (under control for the time being), Hashimotos Thyroiditis and osteoarthritis and...an extremely high LP(a). I won't go into the countless things I have tried and practitioners I've seen (both medical and "alternative") over the past 20 years. The ulcerative colitis was very severe, I was in the hospital for 2 weeks and they wanted to remove my colon (2010). The Hashimotos has been controlled with meds.

A few weeks ago I wanted to try Pauling's protocol. Every time I take the proline and lysine, (vitamin c is fine) I get horrible bloating, abdominal pain and constipation - it's as if one or both of them is not digesting. When I stop taking them, the problem ceases, when I try again, the problem starts again. I am not sure which one - or both - might be causing the problem. I tried to take the HCL with pepsin and some enzymes for digestion. They seemed to help (not so sure) but I really shouldn't take them because of the UC and the antiinflammatory (Balsalazide) I am taking. I am also losing my hair rapidly now and I have no idea why.

I must get this LP(a) level down. My LDL is slightly high, HDL good, total cholesterol a little high, but my LP(a), despite these other levels being normal, has been high for several years and no one paid any attention. I had a VAP test, which I sent to you in one of my prior emails.
By the way, I am a medical provider and a medical writer/journalist; albeit, unemployed at the moment.
Thanks,
R

Stop the proline - and try slowly working up the lysine to about 5 or 6 grams.

Proline's main action seems to be reducing Lp(a) but the first order of business in my opinion in your case is neutralizing Lp(a) - the Lp(a) binding inhibitor function described in the Pauling/Rath patents.

What is your Lp(a) number and how was it measured? VAP Lp(a) number would be great.

Have you read Brownstein's latest edition of IODINE - Why you need it and why you cannot live without it?

I would be interested in your experience with Iodine regarding these conditions.

[exitium]

The fact there is ulcerative colitis would have me looking for intestinal pathogens. When the gut is out of whack it makes everything so much harder.

[ofonorow]

Thanks. I also sent you another email too. I just noticed the part of your last email about the Iodine book. I will look into that. Right now though, I am more concerned with my GI symptoms; I don't think I am absorbing much because of my bloating, indigestion, constipation that started a few weeks ago. The lysine (or proline) was exacerbating it. I think this is why I am losing my hair.
I am also confused about my LP(a). I just got an email from my provider telling me that I do not need to be concerned about the LP(a) (really the one a year ago which was the VAP) because I have the "large Type A buoyant particles."
That is not what I understand from reading the VAP. I have attached it here. Can you tell me what these mean? (I know what some of means, of course, but I do not know what large A buoyant particles are.)
Thanks,
R

[Lab


,
i
VAP
Cholesterol
Profile


LDL Cholesterol H 141 < 130

HDLCholesterol 74 >=40

VLDL
Cholesterol 21 < 30

---~--------...-~~-~_I022=~----~------~----=-~-----~
Cholesterol,Total 237 < 200
H



Triglycerides 93 < 150

Non HDL Chol 162 H < 160

H
apoB1OO-calc 104 < 109

LDL-R 99 < 100
(Real)-C


Lp(a)
Cholesterol 25 (< 10)
H


IDLCholesterol 17 < 20


Remnant 30 < 30
Lipo.
(IDL+VLDL3)


Probable
Metabolic
No
No
Syndrome


,
HDL-2 24 > 15
(Most
24
i022
Protective)
I


HDL-3 50 > 25
(Less
50
1022
Protective)
!


VLDL-3 13 < 10
(Small
H
13
mg/dL
<10
022
Remnant)
1


LDL1 33.7
Pattern
33_7
mg/dL
1022




Vitamin
D,
25-Hydroxy


Source:
BLOOD-Patient
Collected:
07/30/2012
1:38
PM


VitaminD,25- 49.1
Ing/mL
30.0Hydroxy
,
100_0


Vitamin
D
deficiency



1.
10M

[Johnwen]

Without knowing his medical history it appears to be a liver problem cooking here.

The stomach problems, the high HDL, the low IDL, the large Type A buoyant particles, The slightly elevated VLDL all kind of point to “ Hepatic lipase deficiency. “ Which is a somewhat rare condition but seeing low triglycerides pretty much confirms it.

The good news is there is evidence of a delay in atherosclerosis with this condition.

The slight elevation in LP(a) would also be characteristic of a BLEED somewhere in the system. Which I suspect is in the digestive system.

I would suggest he research, “ Hepatic lipase deficiency “ and have a talk with his doc about this possibility and he would probably refer him to a hepatologist for an evaluation on what to do that would help.

[rachel100639]

Dr. Wen,
I am a "she." I do not have any internal bleeding. I have been checked for that just recently. Lab for all iron, hgb, hct, etc., are WNL. Fecal stool neg for blood.
I started taking another enzyme preparation and sweetish bitters. I am starting to feel better - like my food now is digesting. I have also cut out all gluten. No more nausea or gas/bloating/pain.
But I will look up hepatic lipase deficiency.
Thanks,
Rachel

[rachel100639]

Dr. Wen,
Plus, that VAP was done 8/2012. If I was bleeding all this time, I would be in trouble. All CBC's have been normal since then. I am getting another VAP this week.
Rachel

[ofonorow]

I forgot something important.

I had started taking Zoloft about 2 years ago for debilitating anxiety. I wanted to get off of it so I stopped it about a month ago. I had forgotten that it had really helped my gut. Yes, sounds odd, but it's true. There are more serotonin receptors in the gut than in any part of the body. A week ago, because of these horrible gut issues, and some anxiety I went back on it. Is it the Zoloft that is helping? Is it because I am not taking the proline? Is it because I stopped taking those other supplements? Is it stress? Is it because I cut my estrodial patch in half (my hair started falling out 5 months ago when I started this patch) Is it because I changed to another fish oil brand? I don't know. ):
Rachel

then

I guess I spoke too soon. I am still having the same symptoms.
Rachel

[Johnwen]

Rachel;
See if your doc would order a Lipase (LPS) and Amylase (AMY) and LP(a) test for you to see where your at now.
This would get you a better idea whats going on here, now!