Moderator: ofonorow
storm wrote:Ohhh no !!
http://news.bbc.co.uk/2/hi/health/7971414.stm
The study appears in the New England Journal of Medicine.
J.Lilinoe wrote:The study appears in the New England Journal of Medicine.
Wonder who funded the study? Astra Zeneca? Perhaps that is why the serious side effects of taking Crestor were left out?
Which serious side effects were left out?
J.Lilinoe wrote:Which serious side effects were left out?
Actually, the first question to answer is, who funded the study? Do you know?
My guess is that it was funded by Astra Zeneca and that is why the study "appears to be" so favorable toward the drug.
As to your question, which serious side effects were left out? I don't know. Do you?
I think that a study using a drug that is listed as "The Most Dangerous Cholesterol-Lowering Statin Drug" should provide both sides of the story, don't you?
The median follow-up time in the trial was just under two years, so obviously the paper cannot report on potential side effects associated with longer term use.
J.Lilinoe wrote:The median follow-up time in the trial was just under two years, so obviously the paper cannot report on potential side effects associated with longer term use.
And since the study only lasted less than 2 years, and since it is assumed that patients will take the drug long term (more than 2 years) then the study is only good for short term use and is actually pretty useless for long term use IMO.
J.Lilinoe wrote:Furthermore, I think we should expect studies using Crestor to always last less than 2 years because anything longer would actually reveal all those nasty side effects. But these studies should never be used to justify long term use IMO.
safety monitoring board decided that there was a clear benefit associated with statin therapy,
ofonorow wrote:safety monitoring board decided that there was a clear benefit associated with statin therapy,
"clear benefit" ??? You have seen the graph, especially lower graph, right? http://vitamincfoundation.org/images/graph.png
The reason the JUPITER trial was stopped early was because the independent data and safety monitoring board decided that there was a clear benefit associated with statin therapy, and that patients in the placebo arm should be offered the treatment.
J.Lilinoe wrote:The reason the JUPITER trial was stopped early was because the independent data and safety monitoring board decided that there was a clear benefit associated with statin therapy, and that patients in the placebo arm should be offered the treatment.
That's the flimsy reason that the drug companies love to use in order to fool people and keep them from knowing that if the study were to last a life time, the benefits would be dwarfed by all those harmful, nasty side effects.
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