Side effects of Lysine Raise Cholestrol????

The discussion of the Linus Pauling vitamin C/lysine invention for chronic scurvy

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jknosplr
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Side effects of Lysine Raise Cholestrol????

Post Number:#1  Post by jknosplr » Fri Jan 07, 2011 8:36 am

Found this piece in the link below. I have read posts here that when people start the protocol that their cholesterol increases could lysine be the reason :?:

http://www.bodybuildingforyou.com/health-supplements/l-lysine-benefit-side-effects.html

Lysine Supplements
This is one of those amino acids for which a deficiency is very rare, if the diet contains sufficient protein. Signs of a lysine deficiency include fatigue, nausea, dizziness, appetite loss, anxiety, decreased immunity and slow growth. People who have inadequate protein intake, and strict vegetarians (vegans) whose diets lack legumes and don't include a wide variety of foods, may need more lysine and amino acids in general. In that case, a supplement that provides a combination of amino acids would be a better choice than single amino acid supplements. The chances of creating an amino acid imbalance in the body are greater when taking single amino acids, and imbalances can interfere with the absorption of dietary amino acids.
The estimated adult requirement for lysine is 12 milligrams per kilogram of body weight. Again, as with some of the other amino acids, some experts feel that the requirement is set too low. The National Academy of Sciences acknowledges that the state of knowledge concerning amino acid requirements is "unsatisfactory" and expresses the hope that continuing research in the field will yield additional information for consideration. There is no information on the specific amino acid requirements for pregnant or lactating women, and the requirements for older people are considered to be the same as for younger adults.
Lysine Side Effects

Lysine supplements appear to be nontoxic, but they're not without side effects. In general Lysine supplements are considered safe, and there are few reported side effects of Lysine. Some L-lysine side effects include:
lysine can increase cholesterol and triglyceride levels in the blood. People at risk for cardiovascular disease, or who already have elevated cholesterol and triglyceride levels, should definitely talk with their doctors before taking lysine
High doses of lysine (more than 10g/day) can cause nausea, stomach cramps, and diarrhea

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Re: Side effects of Lysine Raise Cholestrol????

Post Number:#2  Post by majkinetor » Fri Jan 07, 2011 10:47 am

Its true and it seems to be temporal trend. Since Lysin acts like "teflon" agent besides its role in collagen formation, it will remove cholesterol depots from the blood vessels and those will show in the blood.

As opposed to proline, lysine is an essential amino acid, which means that the body cannot synthesize it. Daily supplementation of this amino acid is, therefore, critical.
Lysine, like proline, is an important building block of collagen and other stability molecules, and its intake helps to stabilize the blood vessels and other organs in the body. The combined intake of lysine and proline with vitamin C is of particular importance for the optimum stability of body tissue.
For optimum strength of the collagen molecules, its building blocks lysine and proline need to be bio-chemically modified to hydroxyl lysine and hydroxy proline. Vitamin C is the most effective biocatalyst for accomplishing this “hydroxylation” reaction and, thereby, for providing optimum strength to the connective tissue.
Lysine is another “Teflon” agent, which can help release deposited fat globules from the blood vessel deposits. Lysine is also the precursor for the amino acid carnitine. The conversion of lysine into carnitine requires the presence of vitamin C as a biocatalyst. This is another reason why the combination of lysine and vitamin C is essential.
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Now, my only question about this is - isn't this supposed to rise HDL instead LDL since it is the protein responsible for bringing cholesterol back to liver ?

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Re: Side effects of Lysine Raise Cholestrol????

Post Number:#3  Post by ofonorow » Sun Jan 09, 2011 12:35 am

Now, my only question about this is - isn't this supposed to rise HDL instead LDL since it is the protein responsible for bringing cholesterol back to liver ?


If LDL on the arterial wall is being "released" by lysine/proline back into the blood stream, its function would be irrelevant, right?
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