Does splitting the dosage reduce GI side effects?

This forum will focus on the interesting topic of titrating oral vitamin C intake to so-called bowel tolerance, the point just prior to the onset of diarrhea

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poisade1
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Does splitting the dosage reduce GI side effects?

Post Number:#1  Post by poisade1 » Fri May 11, 2012 8:17 am

I got your message Owen and forwarded it to my friend. I, as I may have mentioned was taking 5gms./day all at once. I started to have some GI effects, so I cut back to 4gms. I no longer need the Prozac, and have cut way back on the Ritalin as well as the Xanax. Could I avoid the GI effects and go back up to 5 gms/day by splitting the dosage times?

Also, I beleive I could benefit greatly by adding the GSH, but reading in the literature that it has a 'rotten egg' taste due to the sulfur component-I just don't think I could get it down without gagging. That is, unless I could swallow something immediately after to remove the aftertaste. Would doing that effect its efficacy? If so, I'm going to have to search out a B Complex from somewhere else that is just as bio-available as GSH, but in capsule form. Any thoughts?

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Re: Does splitting the dosage reduce GI side effects?

Post Number:#2  Post by ofonorow » Tue May 15, 2012 3:33 am

Yes, splitting the dosage should reduce GI side effects.

According to Hickey/Roberts as described in their book ASCORBATE: THE SCIENCE OF VITAMIN C (lulu.com/ascorbate) the half life of vitamin C in the blood is 30 minutes, and the amount to keep blood levels consistently at their highest is 500 mg every 3 to 4 hours. (For me, this is not convenient so I tend to take my 9000 mg twice per day.)

Getting off drugs is always a plus.

I have noticed that the benefits far outweigh any disadvantage, (judging from the shortage at Livon.) If you take it the proper way - there is NO taste. Tear the Lypo-GSH packet, and drop the contents into a glass filled with just the amount of water or juice you can swallow in one gulp.

Owen R. Fonorow, Orthomolecular Naturopath

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Re: Does splitting the dosage reduce GI side effects?

Post Number:#3  Post by CeeCee101 » Mon Jan 11, 2016 12:37 pm

Personally, I have found to have less GI distress when taking sodium ascorbate every 4 hours instead of every 2 hours, with the same dosage in total.

It could be, because when taking it every 2 hours, it's bound to be taken on a full stomach sometimes. When I take it on a full stomach I get bloated and gassy.


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