New Method for Very High Potency Liposomal Vitamin C

[norma67]

[pounce]

My studies end where all yours end, with the impossibility to test it under a microscope to know the real quantity of encapsulation, but what is most important for me is that it works and does its job.

Thanks for taking the time to post your experiences and process.

I noted assumptions similar to most.

Lecithin products are all different. Can you share the product you are using and perhaps the PC content?

You have not tested your liposomes so you don't know the size of them or quantity, but you feel confident your process produces liposomes of a certain size.

Are you interested in having your projects tested by a lab? In previous posts I've mentioned I'm interested in collaborating and having a group test.

I noticed you use heat for the lecithin to mix. Have you tried mixing the 94% ethanol full strength into the lecithin? I find it melts in a few minutes. No heat needed. I see that you consider the heat important. Do you have any concerns about the high temp impacting the C?

[norma67]

[pounce]

Thank you for that document link. Its very interesting and I hadn't seen it before. I'll try out the method. I'll have to lean more about the transition temperature. I see that there is comment about adding the component was the lipid mixture cools, but just about the tc. They are suggesting 60-70c. I was concerned about oxidation of the C, but I just read some materials on testing the degradation of c at various temps and up in this area for under an hour was maybe 5%. That is probably acceptable.

I've looked around at the various commercial lecithin products meant for the pharma industry and they have some very specific ones with much higher PC content than what you might find as a product meant for consumers. Greater than 50%. I haven't gone so far as to try to obtain any because I would assume they order would need to be substantial.

The article mentions % glycerol. It was my interpretation that the importance was similar to what you are suggesting with the tocopherol. I have seen glycerin as a component of commercial liposomal c. I'm curious if you abandoned the idea of using glycerol for any particular reason.

Thanks again for posting. I believe the contribution is very valuable.

[norma67]

I know there are various products with a high PC content, but since this thread treats a DIY method, I suggest to use a commercial lecithin, which can be easily available.
I have chosen the alcohol because it is easy to find for me, and it has also a conservative effect.
But as I understand in some states the alcohol is not sold, then it could be good alternative to use glycerol (which is also an alcohol).
The tocopherol is lipophilic, as well as the fatty acids (or other oil-soluble vitamins, lipids, cholesterol) and they are entrapped in the oil-like portion of the phospholipid creating a more plastic membrane as well as it has an anti-aggregate effect.
Since the C vitamin is water-soluble, it will attach to the hydrophilic part and by consequence it is protected inside the vesicle when the liposomes are formed.

[pounce]

I know there are various products with a high PC content, but since this thread treats a DIY method, I suggest to use a commercial lecithin, which can be easily available.
I have chosen the alcohol because it is easy to find for me, and it has also a conservative effect.
But as I understand in some states the alcohol is not sold, then it could be good alternative to use glycerol (which is also an alcohol).
The tocopherol is lipophilic, as well as the fatty acids (or other oil-soluble vitamins, lipids, cholesterol) and they are entrapped in the oil-like portion of the phospholipid creating a more plastic membrane as well as it has an anti-aggregate effect.
Since the C vitamin is water-soluble, it will attach to the hydrophilic part and by consequence it is protected inside the vesicle when the liposomes are formed.

I'm looking at various products to try your method. For the tocopherol I am seeing a number of supplements in gelcaps available, but I'm not sure if it makes a difference with d-alpha, beta, delta, gamma types. What type of product are you using or would you recommend?

[norma67]

It is alpha-tocopherol, I have used a pharmaceutical pure E vitamin for cosmetic purpose, which is sold in bottles, it is a dense liquid.
I think the gelcaps can be used as well, though control that it is pure E vitamin, and extracting the content from the caps.

[pounce]

It is alpha-tocopherol, I have used a pharmaceutical pure E vitamin for cosmetic purpose, which is sold in bottles, it is a dense liquid.
I think the gelcaps can be used as well, though control that it is pure E vitamin, and extracting the content from the caps.

Thanks for confirming. I have found bulk d-alpha tocopherol locally.

A tip for finding high percentage PC lecithin is to search for bulk PC powder. It wont be labeled lecithin, but it will be the ingredient. That's how I find 40% and higher PC lecithin.

[norma67]

So you will use the PC powder or common lecithin? remember that it can give different results, it could be an idea to try both and see the difference.
I attend to hear your results.

[pounce]

So you will use the PC powder or common lecithin? remember that it can give different results, it could be an idea to try both and see the difference.
I attend to hear your results.

I'm treating the PC powder as lecithin with 40% standardized PC because that's what it is in my product. Lecithin. The PC is the component of lecithin we are interested in for liposomes. I believe you want about 350 - 400mg for each gram of C. If you don't know what's in your lecithin you can't really guess at the right ratio.

I have in the past used "standard" lecithin from soy and sunflower that makes no claims of PC content.

[gwynnegibbons]

Hi everyone. I have recently purchased an ultrasonic cleaner, but I did not realise until it arrived that it does not have inbuilt heating. My question is, does this mean the process cannot be done successfully? From reading Chris' site, it seemed the heat was primarily to dissolve the lecithin into the alcohol/water mixture. Could I therefore do this separately and continue on with the process? Many thanks!

[pounce]

Things heat up from the sonication. You can if you desire simply put hot water in the bath.

[dazed1]

Hi guys, i would like to know how much vitamin c are you actually getting from the high potency vitamin c method,

Is it 16% - the end result? or like 1 gram liposomal c from 6ml solution?

Also one more thing, i will be using sunflower lecithin, does this contain vitamin e, and further improve the shelf life - and efficacy of the product?

Is 1 month way to long maybe and i should aim for 2 weeks batches instead of 1 month? how much of a degradation should this 30 days do? thanks.

[Marcus River]

So I am wondering what your thoughts are on using liquid sunflower lecithin and mixing it with some 200 proof alcohol (as described in the patent) to act as a preservative and then adding to the Vitamin C & Water mix? Where in the USA does one purchase 200 proof alcohol (that's relatively cheap) which is fit for consumption?

[pounce]

Hi guys, i would like to know how much vitamin c are you actually getting from the high potency vitamin c method,

Is it 16% - the end result? or like 1 gram liposomal c from 6ml solution?

Also one more thing, i will be using sunflower lecithin, does this contain vitamin e, and further improve the shelf life - and efficacy of the product?

Is 1 month way to long maybe and i should aim for 2 weeks batches instead of 1 month? how much of a degradation should this 30 days do? thanks.

Weigh all parts of the mix by grams. Divide the total weight by number of grams of C. That is weight of one gram of C liposomal. If you want to convert it to volume weigh it out.

I personally would not use any lecithin where you don't know the PC content or any other content.

I keep it in the fridge. I don't feel 1 month is unreasonable.