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 Correlation of Bowel Tolerance to Health Questionable for me 
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Vitamin C Expert
Vitamin C Expert

Joined: Fri Sep 10, 2010 8:36 am
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Post Re: Correlation of Bowel Tolerance to Health Questionable for me
Absorption of oral vitamin C is 5-15%. Lipo is 100%. Hence, around 6 would probably be enough, not more then 8.

BTW, if C gets absorbed, it still doesn't mean it will enter the cell, insulin resistance for instance may be in effect. Lipo doesn't need receptors.


Thu Oct 20, 2011 4:52 am
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Contributor
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Joined: Thu Mar 10, 2011 5:34 pm
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Post Re: Correlation of Bowel Tolerance to Health Questionable for me
That is also an incredible amount of money to spend! I myself can not afford that. VC capsules ( 1,000 mg) are relatively inexpensive and especially inexpensive for those with higher BT's.


Thu Oct 20, 2011 4:54 am
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Ascorbate Wizard
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Post Re: Correlation of Bowel Tolerance to Health Questionable for me
Quote:
Absorption of oral vitamin C is 5-15%


I am sorry, but again, this number is news to me. Pauling estimated 50% and Cathcart 20%, so where does your statement of fact come from? Thx.

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Owen R. Fonorow, Orthomolecular Naturopath


Fri Oct 21, 2011 1:26 am
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Vitamin C Expert
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Joined: Fri Sep 10, 2010 8:36 am
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Post Re: Correlation of Bowel Tolerance to Health Questionable for me
Intakes of 1 to 1.5 grams results in 50% absorption, but at intakes over 12 grams only 16% of the vitamin is absorbed. In contrast, an intake of less than 20 mg, has a 98% absorption rate. Since most of people here take tea spoon which is between 3 and 4 grams, absorption is around 30% or so. This is tested in healthy people, with GI stress this drops down. With aging you have to consider helicobacter and other stuff.



There are some papers:

http://onlinelibrary.wiley.com/doi/10.1 ... 9/abstract
A two-compartment disposition model of ascorbic acid (AA) pharmacokinetics with saturable and time-constrained intestinal absorption was developed. The model was fitted to pharmacokinetic data obtained after oral administration to nine healthy volunteers of two effervescent dosage forms differing in AA content: Celaskon 60 mg (CK60) and Celaskon 500 mg (CK500). It was demonstrated that in the case of CK500 less than 30% of the dose was absorbed as compared with CK60.

In Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance. they say that 1.25g is between 30% - 50%.


OK, its definitely not 5%, but its far from 50% either. It looks like Cathart was right with 20%.


Fri Oct 21, 2011 1:45 am
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