Re: Correlation of Bowel Tolerance to Health Questionable for me
Intakes of 1 to 1.5 grams results in 50% absorption, but at intakes over 12 grams only 16% of the vitamin is absorbed. In contrast, an intake of less than 20 mg, has a 98% absorption rate. Since most of people here take tea spoon which is between 3 and 4 grams, absorption is around 30% or so. This is tested in healthy people, with GI stress this drops down. With aging you have to consider helicobacter and other stuff.
There are some papers:http://onlinelibrary.wiley.com/doi/10.1 ... 9/abstract
A two-compartment disposition model of ascorbic acid (AA) pharmacokinetics with saturable and time-constrained intestinal absorption was developed. The model was fitted to pharmacokinetic data obtained after oral administration to nine healthy volunteers of two effervescent dosage forms differing in AA content: Celaskon 60 mg (CK60) and Celaskon 500 mg (CK500). It was demonstrated that in the case of CK500 less than 30%
of the dose was absorbed as compared with CK60.
In Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance. they say that 1.25g is between 30% - 50%.
OK, its definitely not 5%, but its far from 50% either. It looks like Cathart was right with 20%.