Most people can absorb
approximately 200 mg. Meaning that the rest comes out in the urine.
There have been few studies conducted to determine the efficiency of ascorbic acid absorption in humans. Differences in the extent of its absorption among individuals may contribute to the outcome of clinical trials. Ascorbic acid absorption in four subjects was investigated from several oral dosage forms containing 1 g of the vitamin (solution, tablet, chewable tablet, and timed-release capsule. Approximately 85% of an intravenous dose was recovered in the urine as ascorbic acid and its major metabolites. In contrast, only approximately 30% of the dose was recovered from the solution and tablet forms. A considerably smaller fraction of the dose (approximately 14%) was recovered from the timed-release capsule. There was considerable intersubject variation in ascorbic acid absorption and there appeared to be good and poor absorbers of the vitamin. Consideration should be given to the influence of the extent of ascorbic acid absorption on the results of clinical trails.
"If a large amount of vitamin C is taken, 62 percent of the amount that enters the bloodstream is excreted in the urine, so that only 38 percent remains in the body to carry on its valuable functions. It is, however, good to have vitamin C in the urine. It protects against urinary infections and also against cancer of the bladder." (Pg. 91)
"A person who eliminates a smaller fraction of the ingested ascorbic acid may do so either because he or she has been living on a diet containing an insufficient quantity of the vitamin, such that the tissues are depleted, or beccause some biochemical abnormality of his or her body operates to remove ascorbate from the blood serum very rapidly, perhaps by converting it rapidly into other substances."
ofonorow wrote:I hope we can get an answer from either
Dr. Hickey or Dr. Roberts ...
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