1910, he writes concerning this case: “By the way, that case of encephaloid breast cancer is alive and free from recurrence----diagnosed October, 1908. I saw her on November 29, as near as mortal man can say ‘cured.’ Further comment on the above is not needed.
I was well aware, as any scientific man is, that negative results in scientific experiments never proved anything at all in science, but was also under the impression that very many scientific discoveries of great moment had been the outcome of single successful experiments. The fall of an apple from a tree revealed the law of universal gravitation to Newton. In our own day a single photographic impression of some keys, etc., led the physicist Röntgen, in 1895, to the discovery of the Röntgen, or X rays; and, strange to say, the find of a few stray ganglion cells in the development of an American lake-fish in 1888 led the writer ultimately to the discovery of the nature of cancer, and of much besides. The scientific investigator knows, even if some surgeons be ignorant of it, that very many discoveries in science are the outcome of what at first were of the nature of single successful experiments. Even the cures* of cancer by
*Looking at the matter from the point of view of practical embryology, the so-called cures” of cancer by surgical operation are probably in all cases without exception examples of the “cure” of a benign tumour, a more or less reduced “ embryoma.” Naturally benign tumours are of common occurrence, and whether diagnosed by microscopical examination or only clinically, the diagnosis of cancer is not one which can be regarded as conforming to a scientific criterion. When one thinks of the extraordinary frequency of recurrence after surgical operation, one can only conclude that, in the absence of the crucial stereo-chemical tests, either of adequate injections of sufficiently potent preparations of trypsin and amylopsin, or of examination of the tumour albumins by means of the polarimeter, at present there is no valid evidence extant that operation has ever cured a single case of malignant disease, though it may quite well have induced it. as the X rays have often done. Sir James Paget, a scientific